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In the myotatic knee-jerk reflex, what would happen if the α motoneurons to the hamstrings were severed?


A) The lower leg would tremor.
B) The thigh would tremor.
C) The Golgi tendon organ would experience exaggerated stretch.
D) The intrafusal muscle fibers would extensively.
E) The extrafusal muscle fibers would stop firing.

F) B) and E)
G) D) and E)

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Describe or draw the inter-relationships in how the motor cortex, pre-frontal cortex, basal ganglia, cerebellum, spinal cord and brainstem are involved a movement.

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Thinking of initiating a movement begins...

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One of the main hallmark clinical symptoms of Parkinson's Disease is uncontrolled tremors throughout the body. This strongly indicates that this disease involves the


A) cerebellum.
B) motor cortex.
C) corticospinal tract.
D) basal ganglia.
E) red nucleus.

F) A) and E)
G) A) and D)

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Which projection from the cerebellum indicates that it is involved in fine motor control?


A) To the motor cortex
B) To the vestibular nuclei
C) To the reticular nuclei
D) To the sensorimotor cortex
E) To the spinal cord

F) B) and C)
G) B) and E)

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One of the main benefits of α and γ motoneuron coactivation is to


A) provide constant feedback to the brain regarding muscle tension and length.
B) prevent injury to the muscle because if stretched too much, it will resist stretch.
C) provide greater flexibility of the muscle.
D) provide the muscle with greater strength.
E) allow the muscle to hypertrophy.

F) None of the above
G) A) and B)

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If a skeletal muscle fiber is excised from the body, mounted between two immovable plates, and then concentrically stretched (lengthened) , which will respond more than the other (in terms of firing action potentials) ?


A) A (alpha) motoneurons will respond more than γ motoneurons.
B) Γ motoneurons will respond more than α motoneurons.
C) A (alpha) and γ motoneurons will respond to the same extent.
D) Neither α nor γ motoneurons will respond in this artificial setup.
E) It depends on how much stretch is employed.

F) B) and E)
G) C) and D)

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Recordings of extrafusal muscle tension and accompanying sensory discharge from muscle spindles reveal that


A) stimulation of α motoneurons is required to elicit a response from fusiform γ efferents.
B) fusiform efferents respond when extrafusal muscle fibers are relaxed.
C) fusiform efferents respond only if extrafusal muscle fibers are stimulated.
D) intrafusal muscle fibers' work load is proportional to that of the extrafusal muscle fibers.
E) intrafusal muscle fibers exhibit either maximum tension or none at all, depending on the tension experienced by the extrafusal muscle fibers.

F) A) and E)
G) B) and C)

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Experiments by Georgopoulos showed that visually guided arm movements are initiated by corticospinal neurons that were selective for


A) angle.
B) age.
C) activity.
D) proprioception.
E) direction.

F) A) and B)
G) None of the above

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Which of the following represents a key feature of the reticulospinal tract?


A) It controls locomotion, balance and posture.
B) It is one of the major lateral descending pathways.
C) It descends only as far as the cervical spinal cord.
D) It controls fine motor skills of the distal limbs.
E) It controls crude motor skills of the proximal limbs.

F) All of the above
G) B) and E)

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Reciprocal innervation means that contraction of one muscle set is accompanied by


A) relaxation of an antagonistic muscle.
B) stimulation of a downstream muscle.
C) stimulation of its downstream Golgi tendon organs.
D) inhibition of an antagonistic muscle.
E) stimulation of an antagonistic muscle.

F) A) and D)
G) A) and E)

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The flexor reflex is also often called the "withdrawal reflex". This is because it


A) is a polysynaptic reflex arc.
B) is life-preserving or causes avoidance of an aversive stimulus.
C) causes the animal to withdraw into isolation.
D) involves each side of the body, one at a time.
E) involves both sides of the body, sequentially.

F) C) and D)
G) A) and B)

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Explain what happens to a muscle when it stretches.

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When a muscle stretches, not only are ex...

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Central (CNS) awareness of muscle stretch occurs because of


A) stimulation of α motoneurons.
B) stimulation of γ motoneurons.
C) relaxation of α motoneurons.
D) relaxation of γ motoneurons.
E) stimulation of both α and γ motoneurons.

F) A) and E)
G) B) and E)

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Which of the following describes the action of dopamine on striatal neurons of the direct and indirect paths, respectively?


A) Facilitates activity, suppresses activity
B) Facilitates activity, no effect on activity
C) Suppresses activity, facilitates activity
D) No effect on activity, facilitates activity
E) Suppresses activity, no effect on activity

F) C) and D)
G) B) and E)

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In the ubiquitous reaction, H2O + CO2 ↔ H2CO3 ↔ HCO3- + H+, found in the blood, explain how a build-up of protons in the blood leads to increased carbon dioxide in the CNS.

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Protons cannot cross the blood-brain bar...

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In physical movements that require a lot of stretching (e.g., yoga) , which of the following will respond more than the other (in terms of firing action potentials) ?


A) A (alpha) motoneurons will respond more than γ motoneurons.
B) Γ motoneurons will respond more than α motoneurons.
C) A (alpha) and γ motoneurons will respond to the same extent.
D) Neither α nor γ motoneurons will respond in this artificial setup.
E) It depends on how much stretch is employed.

F) A) and B)
G) A) and C)

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The muscles on which strength training (e.g., power-lifting, weight-lifting, resistance training) depends would


A) be large.
B) have high endurance capacity.
C) be highly vascularized.
D) have high myoglobin content.
E) have relatively high oxidative capacity.

F) A) and B)
G) A) and C)

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The origin of the corticospinal tract is in the


A) cerebral cortex.
B) visual cortex.
C) frontal cortex.
D) lateral spinal cord.
E) medial spinal cord.

F) B) and D)
G) A) and D)

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